“Cerebros del patio trasero” visita a Tejas del Oeste y lleva potenciales de acción al desierto

We are proud to have run many workshops in the Midwest, but co-founder Tim has longed to bring spikes to the Texas plains he recalls from his early years (he graduated from high school in El Paso and went to college in Austin). Thus, it was with great delight when Emily Verla Bovino, artist-in-residence with Fieldwork: Marfa and graduate researcher at UC-San Diego, invited Backyard Brains to come down and help run a workshop at Marfa Independent High School, deep in West Texas.  To those not in the know, West Texas has the least light pollution in the lower 48 states, is terrific for astronomical observation, and is the “kind of Texas” you’d imagine if you’ve never visited.
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photos by Backyard Brains

The Marfa High School visit ran over two days the week before Christmas. The school is rather small with a total enrollment of ~100 students, so in a marathon session facilitated by Emily and both the arts and physics teachers, Tim lectured to all four classes: Freshman at 8 AM, Sophomores at 9 AM, Juniors at 10 AM, and Seniors at 11 AM! He presented principles of neurotechnology interspersed with neural recording and stimulation experiments, closing with a brief discussion of entrepreneurship.

Following the lectures/demos on neuroscience, the workshop began in the afternoon, where with the organization of art teacher Ellie Meyer, the sixteen students of teacher Benjie Rosaldo’s Robotics Class learned about analog electronics and built their own SpikerBoxes. This took place over two afternoons, and after we identified and fixed the usual errors of shorts and the occasional incorrectly-placed resistors, we concluded with the cricket drug experiments and demo’s of the RoboRoach.  Some of the students learning the art of ranching part-time, we noted the comfort level with the bugs was higher than other workshops we have run…

photos by Emily Verla Bovino

During the second day of the workshop, we also had a live radio interview along with students Zach Madrid and Eileen Cordova. You can listen to our interview with station manager Tom Michael on KRTS Marfa Public Radio below:

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Notably, our spikes in the studio were transmitted live across the land! A running joke from our graduate school days, and even today, is the question we often receive: “Have you ever thought of making your [insert invention/technique here] wireless?” For example, a “wireless” SpikerBox would interface with a computer or smartphone without the need of a cable. We hereby announce that “Yes We Can. The SpikerBox can go wireless!” By hooking up the SpikerBox to Marfa Public Radio’s 5,000 Watt radio tower, Spikes were broadcast over 15,000 square miles to listeners in the West Texas desert. Contact us if you are interested in purchasing your own 5,000 Watt Radio Tower to accompany your SpikerBox, but be aware of certain FCC regulations

photo by Backyard Brains

During our stay in Marfa, Emily’s three month residency at Fieldwork: Marfa was at its end.  Her artistic “fieldwork” involved research for an episode in the epic life-log of a fictional character that Emily calls the “hyperthymestic RK”. In the episode, the second of a never-ending series  (contact her if you would like a screening of the first installment online at rk-log.net) the character RK travels to a heterotopian West Texas of the near future to participate as a human subject in clinical studies. Emphasis in these studies is on neural engineering, specifically optogenetics and nanorobotics. The scenario for episode two, a scenography and audio-drama which Emily is now in the process of editing, was presented at the local Honky Tonk Bar “Padre’s”, an initiative owned and run by the multihyphenate David Beebe. We ran some demos of spikes to set the scene for a story of unmanned border check points patrolled remotely with battling transgenic beetles and cockroaches engineered in neurotech land yacht flexlabs.

Photo by Backyard Brains

The whole visit was quite fruitful on both the art and science fronts, and we are exploring how to make our visit to West Texas a yearly Fall tradition. West Texas, with it’s unique geography and open skies, has an expansive effect on the mind that many brain-workers, including the cosmologists Donald Judd and Carl Sagan, have been attracted to. Thus, with Emily, we are brainstorming ways to begin a “Looking Outward, Look Inward” yearly fall workshop. West Texas already has the famous McDonald Observatory to understand the universe beyond, so why not also make the borderlands a place to understand the universe within?

Unique work spaces are abundant in West Texas and should appeal to the numerous DIYbio groups that have cropped up across the country in recent years. As the trip wound down, Emily arranged for Tim to run experiments in Padre’s vintage airstream land yacht on ranch land just a few miles west of the landmark Marfa eateries Mando’s and Alice’s Cafe.  Though Tim didn’t get the chance to taste Mando’s chile rellenos or Alice’s huevos rancheros, he did eat a “Marfa burrito”, went hunting for “fragile cockroaches”on the banks of the Rio Grande and even got to debug student boards with unidentified circuit shorts in the airstream.

Stay tuned. ¡Bienvenidos al futuro! ¿Que descubrimientos de los picos, nos esperan en el porvenir?

Photo by Backyard Brains

Photo by Emily Verla Bovino

Acknowledgements: We thank the Burns Family, Marfa Studio for the Arts, Fieldwork: Marfa, The Marfa National Bank, and Padre’s Marfa for sponsorship and support.

Posted: 2012-Jan-25 — Filed under: Education,Marketing,Outreach — Tags:

2-Channel SpikerBox Now Available. Measure Neuron Speed in Earthworms.

We hereby announce our 2-Channel SpikerBox. What can you do with it? Why, you can measure the speed of spikes as they travel down a nerve, in a truly “backyard” preparation using Earthworms. See our full experiment write up on how to do it! How fast is a spike? Faster than a car, faster than a plane, faster than a speeding bullet? Find out!

Posted: 2012-Jan-10 — Filed under: Education,Hardware,Marketing — Tags:

Backyard Brains Returns to the Nature Neuroscience Podcast, unveils Optogenetics Prototype

Coming to the Society for Neuroscience meeting is always great fun for us, and it was especially true this year as we unveiled the third generation of our optogenetic prototype and actually did some experiments at our poster! Earlier this year we sponsored a student design effort to build a portable optogenetic rig using cholinergic ChR2 (Channelrhodopsin) transgenic fruitfles from our collaborator Stefan Pulver. We’ve been hard at work over the summer improving the prototype with two design cycles, and here is version 3.

We brought the prototype to SfN; Stefan brought the special flies. Here at Backyard Brains we believe in real-time posters, so if you came by, you would seen us explaining how the prototype worked while Stefan was busy preparing the fruitfly larva for recording. Below Nature reporter Ewen Callaway talks to Stefan as he tries to use our micro-rig.

Ewen subsequently wrote a nice blog post on our gear for the Nature News site, but the best treat of all for us was returning to “Neuropod,” the Nature Neuroscience podcast. We were on the podcast three years ago when we first tried to present our gear and nothing worked. But we kept hacking away, and now, with all our gear fully operational, we were happy to bring the first spikes recorded live on Neuropod!

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As astute listener may wonder why you only hear the standard cockroach leg spikes on the podcast. Where are the fruitfly muscle recordings? Weren’t we also talking about some optogenetic device? Show the data! We admit, it was still relatively early in the day when we spoke with Ewen, and Stefan was still trying to get his dissection right (he remarked the monocular microscope made the dissection difficult, and he would have preferred the gooseneck dissection lights to be longer. Noted for Gen4). But Stefan stayed focused, and at 2 PM Sunday afternoon we successfully recorded the critical piece of data: the electromyogram from the fruitfly muscle during presentation of blue light. It’s noisy, but in the recording below you can hear the increased activity from the muscle at ~2 seconds when Stefan turned on the blue light. The blue light caused the cholinergic motor neurons to depolarize, resulting in muscle contraction.

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Expect us to release the designs for the micromanipulator (you could 3D print it yourself!) and LED control circuit in a month or so.

It was a busy SfN for us, as we also ran a symposium on “Low Cost Neuroscience” with our colleagues Bruce Johnson from Cornell, Jeff Wilson from Albion, a high school teacher from the D.C. area, Raddy Ramos from New York Institute of Technology, our friend Stefan, and our keynote speaker Ben Robbins, a 6th grader from Novi Meadows Middle School. Mr. Robbins taught the audience how to successfully do outreach to 5th graders. We don’t have access to age data of presenters at SfN, but we would venture to guess Mr. Robbins may have been the youngest presenter ever for the society.

Scientists, with their huge intellect and famous experiments, can sometimes be intimidating to approach. Thus, we were a bit cautious and sheepish when we asked Mr. Robbins if he would let us take a picture with him. Thankfully, he was cool with it.


Photo by Jeff Wilson

You can watch Mr. Robbins’ talk below in all its lo-fi hand held camera glory. Don’t worry, the shaking slows down about 20 seconds in.

Our good friend Moheb Costandi also wrote a detailed summary of the symposium for the Dana Foundation. Stay tuned in the months to come as we release more inventions!

Posted: 2011-Dec-09 — Filed under: Hardware,Marketing

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